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CI # 51521 Which patients with metabolic syndrome benefit from initiation of metformin?: search

Search Summary

Cochrane Library - CDSR (Systematic Reviews)

0 metformin and (prediabetes or diabetes prevention or metabolic syndrome)
Cochrane Library - Other Systematic Reviews (DARE) 1 Treating prediabetes with metformin: systematic review and meta-analysis (structured abstract) Original article:Lilly [Lily] M, Godwin M. Canadian Family Physician.2009;55(4):363‐369
PubMed

Systematic reviews & meta analyses

17 metformin/tu[mh] AND (diabetes mellitus/pc[mh] OR metabolic syndrome x/pc[mh]) AND (Meta Analysis[pt] OR meta analy*[tw] OR metaanaly*[tw] OR systematic review*[tw] OR data synthesis[tw] OR data extraction[tw] OR Cochrane Database Syst Rev[ta]) AND english[la]
PubMed

RCTs; duplicates removed

68 metformin/tu[mh] AND (diabetes mellitus/pc[majr] OR metabolic syndrome x/pc[majr]) AND (randomized controlled trial[pt] OR (random*[tw] NOT medline[sb])) NOT (Meta Analysis[pt] OR meta analy*[tw] OR metaanaly*[tw] OR systematic review*[tw] OR data synthesis[tw] OR data extraction[tw] OR Cochrane Database Syst Rev[ta]) AND english[la]
PubMed

Guidelines; duplicates removed

2 metformin/tu[mh] AND (diabetes mellitus/pc[mh] OR metabolic syndrome x/pc[mh]) AND (Guideline[pt] OR Practice Guideline[pt] OR Consensus Development Conference[pt] OR Consensus Development Conference, NIH[pt]) AND english[la]
National Guideline Clearinghouse 1

Diagnosis and management of type 2 diabetes mellitus in adults. Redmon B, Caccamo D, Flavin P, Michels R, O'Connor P, Roberts J, Smith S, Sperl-Hillen J. Bloomington (MN): Institute for Clinical Systems Improvement (ICSI); 2014 Jul. 85 p. [197 references]

 

UpToDate   Guidelines: prevention of type 2 diabetes mellitus
FPIN CIs, PURLS, HDAs  

Does metformin prevent diabetes in at-risk adults? 2013 Clinical Inquiry

Metformin use in adolescents 2013 Clinical Inquiry

What are the long-term benefits of giving metformin to a patient with metabolic syndrome? 2010 Evidence Based Practice Help Desk Answer

How can we keep impaired glucose tolerance and impaired fasting glucose from progressing to diabetes? 2010 Clinical Inquiry

Metformin therapy and diabetes prevention in adolescents who are obese. 2007 Clinical Inquiry

 

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Clinician Authors: Liz Stover, Jessica Chi and Gary Kelsberg

Librarian:  Sarah Safranek

Search Due Date: January 2016

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