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CI # 51541 Does statin therapy alter the risk or progression of dementia?: search

Search Summary

FPIN CIs, PURLS, HDAs 1 Do statins delay onset or slow progression of Alzheimer's dementia?Journal of Family Practice, 54(7) 2005: 626-327.

Cochrane Library - CDSR (Systematic Reviews)

 

Statins for the prevention of dementia. January 2016

Statins for the treatment of dementia. July 2014

Statin withdrawal in people with dementia. [Protocol (incomplete) review in progress]  January 2016

PubMed

Systematic reviews & meta analyses

29 (Hydroxymethylglutaryl-CoA Reductase Inhibitors[mh] OR Hydroxymethylglutaryl-CoA Reductase Inhibitors [Pharmacological Action] OR statin[ti] OR statins[ti]) AND (dementia[majr] OR dementia*[ti] OR alzheimer*[ti]) AND (Meta Analysis[pt] OR meta analy*[tw] OR metaanaly*[tw] OR systematic review*[tw] OR data synthesis[tw] OR data extraction[tw] OR Cochrane Database Syst Rev[ta] OR systematic[sb]) AND english[la]
PubMed

RCTs; duplicates removed

26 (Hydroxymethylglutaryl-CoA Reductase Inhibitors[mh] OR Hydroxymethylglutaryl-CoA Reductase Inhibitors [Pharmacological Action] OR statin[ti] OR statins[ti]) AND (dementia[majr] OR dementia*[ti] OR alzheimer*[ti]) AND (randomized controlled trial[pt] OR (random*[tw] NOT medline[sb])) NOT (Meta Analysis[pt] OR meta analy*[tw] OR metaanaly*[tw] OR systematic review*[tw] OR data synthesis[tw] OR data extraction[tw] OR Cochrane Database Syst Rev[ta] OR systematic[sb]) AND english[la]
PubMed

epidemiologic studies; duplicates removed

53 (Hydroxymethylglutaryl-CoA Reductase Inhibitors[mh] OR Hydroxymethylglutaryl-CoA Reductase Inhibitors [Pharmacological Action] OR statin[ti] OR statins[ti]) AND (dementia[majr] OR dementia*[ti] OR alzheimer*[ti]) AND epidemiologic studies[mh] NOT ((randomized controlled trial[pt] OR (random*[tw] NOT medline[sb])) OR Meta Analysis[pt] OR meta analy*[tw] OR metaanaly*[tw] OR systematic review*[tw] OR data synthesis[tw] OR data extraction[tw] OR Cochrane Database Syst Rev[ta] OR systematic[sb]) AND english[la]
PubMed

Guidelines; duplicates removed

2 (Hydroxymethylglutaryl-CoA Reductase Inhibitors[mh] OR Hydroxymethylglutaryl-CoA Reductase Inhibitors [Pharmacological Action] OR statin[ti] OR statins[ti]) AND dementia AND english[la] AND (Guideline[pt] OR Practice Guideline[pt] OR Consensus Development Conference[pt] OR Consensus Development Conference, NIH[pt] OR practice guidelines as topic[mh])
National Guideline Clearinghouse 1 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 2014 July 1.

Author Information

Clinician Authors: Tess Lang and Jon Neher

Librarian:  Sarah Safranek

Search Due Date: Aug 2016

Manuscript Due Date:

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Librarian Contact Information:

Sarah Safranek, MLIS
Information Management Librarian
safranek@uw.edu
guides.lib.uw.edu/hsl/safranek

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