Evidence-Based Practice
EBP process
The EBP process has 5 steps:
- Ask - Develop a relevant, answerable clinical question
- Acquire - Plan, search & find the best available evidence
- Appraise - Critically appraise articles for validity & applicability
- Apply - Integrate the evidence into practice
- Assess - Evaluate your clinical decision
Plan your search
Before you begin
- Clarify and state your question - see PICO
- List the keywords/terms for PICO
- List the years and languages you wish to include
- Identify the databases most appropriate for your search - see EBP resources
Smart searching tips
If you're running into trouble with your search, this 3-minute video from the Centre for Evidence-Based Medicine is helpful:
Once you have your terms, try to broaden or limit your search.
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Use a set of quotation marks (" ") around phrases such as “cerebral palsy" to prevent Google or other search engines from inserting an 'AND' between the terms.
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Truncate search terms with an asterisk (*) to increase the number of results.
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Limit your search by domains to increase the chances of retrieving pertinent results, i.e. site:rehab, site:gov, site:cms.
Filtered resources
Below are filtered resources, or resources that have appraised the quality of studies and often make recommendations for practice.
Meta-Search Engines
- A meta-search engine is a search engine that searches multiple other search engines simultaneously and combines the results.
- SUMsearchSearch for original studies, systematic reviews, and practice guidelines from PubMed.
- Trip DatabaseUK-based clinical search engine. Trip Pro access not available through UW.
Systematic Reviews and Meta-Analyses
- A systematic review is a literature review focused on a single question which tries to identify, appraise, select and synthesize all high-quality research evidence relevant to that question.
- Meta-analyses are systematic reviews that combine the results of several studies using quantitative statistics.
- Systematic reviews minimize the possibility of bias by using explicit criteria, and expand the relevance of individual studies with limited scope.
- Cochrane LibraryIncludes Cochrane Reviews and other high-quality evidence to inform healthcare decision-making.
- PubMed Clinical Queries using Systematic Reviews filterPubMed search limited to specific clinical research areas.
Evidence Guidelines and Summaries
- Guidelines are systematically developed statements of appropriate care designed to assist the practitioner and patient make decisions about appropriate health care for specific clinical circumstances.
- Guidelines from reputable, authoritative organizations are usually based on the most current, relevant research.
- Guidelines are developed using widely varying standards. Cost may be considered as well as health outcomes.
- Summaries of evidence-based information on a topic are useful as it is difficult for a clinician to analyze all the information in a field.
- Essential Evidence Plus This link opens in a new windowEvidence-based, point-of-care clinical decision support system with guidelines, topics, abstracts, and summaries.
- ECRI Guidelines TrustRepository of objective, evidence-based clinical practice guideline content (registration required).
- Recommendations for Primary Care Practice - USPSTFThe U.S. Preventive Services Task Forces systematically reviews the evidence of effectiveness and develops recommendations for clinical preventive services.
- EPC Evidence-Based ReportsAHRQ through Evidence-based Practice Centers (EPCs) provides comprehensive, science-based information on common, costly medical conditions.
Clinical Research Critiques
- Clinical research critiques are analyses of current clinical research topics to identify their strengths and weaknesses and use a systematic process to do so.
- ACP Journal ClubSummarizes the best new evidence for internal medicine from over 120 clinical journals.
- Family Physicians Inquiries Network (FPIN)Includes Priority Updates from the Research Literature Surveillance (PURLS)
- POEMs (Patient-Oriented Evidence that Matters)Synopses of new evidence filtered for relevance to patient care and evaluated for validity.
- Evidence-Based NursingSearches international healthcare journals and applies strict criteria for the validity of research and relevance to best nursing practice.
Background Information
- Consulting sources such as textbooks for background information are helpful for building knowledge in unfamiliar subject areas.
- ClinicalKey This link opens in a new windowIncludes textbooks, guidelines, images, and drug information.
- AccessMedicine This link opens in a new windowIncludes textbooks, guidelines, images, and drug information.
- Health Sciences eBooksView select titles by A-Z or browse by subject.
Unfiltered resources
Below are sources of unfiltered resources, which are primary sources or original research studies. Consider using critical appraisal worksheets to evaluate the studies.
Research Articles (Randomized Control Trials, Cohort and Qualitative Studies, etc.)
- Case Study - a report on an individual patient with an outcome of interest.
- Case Series – a report on a series of patients with an outcome of interest, no control group involved.
- Cohort study – a report on 2 groups (cohorts) of patients, 1 that received exposure of interest + 1 that didn’t (control), following both for outcome of interest.
- Randomized Control Trial (RCT) – a report about participants who were randomly allocated into experimental or control groups and followed over time for variables/outcomes of interest.
- PubMed This link opens in a new windowBiomedical and health sciences journals from the US National Library of Medicine.
- CINAHL Complete This link opens in a new windowThe Cumulative Index to Nursing and Allied Health Literature.
- EMBASE This link opens in a new windowBiomedical database with strong focus on drugs and pharmacology, clinical medicine, and basic science relevant to clinical medicine.
- Web of Science This link opens in a new windowCitation index for the sciences, social sciences, and arts and humanities.
Research guides
The UW Health Sciences Library offers several Research Guides to help you identify appropriate resources. Or check out UC Berkeley's tips on "Searching Literature More Effectively."
- CINAHL Help GuideCINAHL Complete provides access to the literature in nursing and 17 allied health disciplines dating back to 1937.
- MyNCBIMy NCBI is your personal space on the NLM computer system for saving searches, search results, PubMed preferences, and for creating automatic email alerts.
- PubMed at UWPubMed, developed by the National Library of Medicine, provides access to bibliographic citations to biomedical journal articles, including MEDLINE , and to additional life sciences journals.
- Search by SubjectGain tips on researching in other subject areas by visiting their various subject guides.